{"created":"2023-07-27T07:30:50.410538+00:00","id":1623,"links":{},"metadata":{"_buckets":{"deposit":"80361055-d384-4ab0-90eb-22330df975d5"},"_deposit":{"created_by":20,"id":"1623","owners":[20],"pid":{"revision_id":0,"type":"depid","value":"1623"},"status":"published"},"_oai":{"id":"oai:doshisha.repo.nii.ac.jp:00001623","sets":["4151:8699:4203:4204","4251:7687:7688:8785:7689"]},"author_link":["3506"],"item_1693813220986":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1694497428290":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(理学)","subitem_degreename_language":"ja"}]},"item_1694497507610":{"attribute_name":"学位名（英）","attribute_value_mlt":[{"subitem_degreename":"Doctor of Philosophy in Science","subitem_degreename_language":"en"}]},"item_1694497573527":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"同志社大学"},{"subitem_degreegrantor_language":"en","subitem_degreegrantor_name":"Doshisha University"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"34310","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_3_alternative_title_2":{"attribute_name":"その他（別言語等）のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"下丘に入力する興奮性シナプス伝達の発達に伴った機能調節","subitem_alternative_title_language":"ja"},{"subitem_alternative_title":"カキュウ ニ ニュウリョク スル コウフンセイ シナプス デンタツ ノ ハッタツ ニ トモナッタ キノウ チョウセツ","subitem_alternative_title_language":"ja-Kana"}]},"item_3_date_granted_27":{"attribute_name":"学位授与年月日","attribute_value_mlt":[{"subitem_dategranted":"2020-03-22"}]},"item_3_description_12":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"本研究では、聴覚神経系で入力の統合を担う下丘におけるシナプス伝達特性の生後発達段階における変化について、シナプス電流をパッチクランプ法で計測した。NMDA-EPSCにおいて、聴覚入力開始後に減衰時間が短縮していた。上行性経路からのシナプス伝達では、発達段階に応じて短期シナプス可塑性が変化した。一方で、交連性経路からのシナプス伝達では、発達段階に伴う短期シナプス可塑性の傾向には有意な変化はなかった。","subitem_description_language":"ja","subitem_description_type":"Abstract"},{"subitem_description":"The inferior colliculus (IC) is the primal center of convergence and integration in the auditory pathway. I have measured excitatory synaptic currents (EPSCs) of the neurons in the central nucleus of the IC in response to stimulation of the lateral lemniscus and the commissure of the IC. Before hearing onset, the lemniscus inputs exhibited short-term depression, whereas commissural inputs showed facilitation. After hearing onset, the NMDA-EPSCs exhibited faster decay for both pathways. Furthermore, the EPSCs showed less short-term plasticity in both pathways. These developmental changes may ensure faster and more reliable signal transmission to the IC after onset of hearing.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_3_description_18":{"attribute_name":"フォーマット","attribute_value_mlt":[{"subitem_description":"application/pdf","subitem_description_type":"Other"}]},"item_3_dissertation_number_28":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲第1094号"}]},"item_3_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.14988/di.2020.0000000184","subitem_identifier_reg_type":"JaLC"}]},"item_3_relation_16":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"BC02444160","subitem_relation_type_select":"NCID"}}]},"item_3_relation_17":{"attribute_name":"関連サイト","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_language":"ja","subitem_relation_name_text":"掲載刊行物所蔵情報へのリンク ／ Link to Contents"}],"subitem_relation_type":"isFormatOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doors.doshisha.ac.jp/opac/opac_link/bibid/BB13127446/?lang=0","subitem_relation_type_select":"URI"}}]},"item_3_text_8":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"脳科学研究科"}]},"item_3_text_9":{"attribute_name":"著者所属（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Graduate School of Brain Science"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"北川, 真子","creatorNameLang":"ja"},{"creatorName":"キタガワ, マコ","creatorNameLang":"ja-Kana"},{"creatorName":"Kitagawa, Mako","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-28"}],"displaytype":"detail","filename":"k1094.pdf","filesize":[{"value":"398.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"要旨/abstaract","objectType":"abstract","url":"https://doshisha.repo.nii.ac.jp/record/1623/files/k1094.pdf"},"version_id":"c0d230d6-63bb-46e0-a999-eab99d33f9a1"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-07-01"}],"displaytype":"detail","filename":"zk1094.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"zk1094.pdf","objectType":"fulltext","url":"https://doshisha.repo.nii.ac.jp/record/1623/files/zk1094.pdf"},"version_id":"0acf7821-7956-4cec-a30a-eae9cedc0b7a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"下丘","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"シナプス可塑性","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"発達","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"inferior colliculus","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"synaptic plasticity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"development","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Developmental fine-tuning of excitatory synaptic transmission at input synapses in the rat inferior colliculus","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Developmental fine-tuning of excitatory synaptic transmission at input synapses in the rat inferior colliculus","subitem_title_language":"en"}]},"item_type_id":"3","owner":"20","path":["4204","7689"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-06-01"},"publish_date":"2020-06-01","publish_status":"0","recid":"1623","relation_version_is_last":true,"title":["Developmental fine-tuning of excitatory synaptic transmission at input synapses in the rat inferior colliculus"],"weko_creator_id":"20","weko_shared_id":-1},"updated":"2023-12-20T00:30:04.423381+00:00"}